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Low-Substituted Hydroxypropyl Cellulose Used as Disintegrant for Solid Dosage Forms
Basic information:
Hydroxypropylcellulose (HPMC) is an important synthetic polymer commonly used in pharmaceuticals, building materials, food industry and other fields. The following are the general physical and chemical properties of hydroxypropylcellulose:
Physical properties:
Appearance: Usually white or white-like powdery substance.
Solubility: It has good solubility in water and forms a colloidal solution.
Thermal stability: Under appropriate conditions, it has certain thermal stability and can be used in processes such as thermoforming.
Chemical properties:
Chemical structure: Hydroxypropyl cellulose is polymerized from methacrylate monomers and has functional groups such as hydroxyl and acryloyl groups.
pH stability: Stable under neutral or weakly alkaline conditions. For different grades of HPMC, the pH stability range may be different.
Compatibility with other substances: Generally good compatibility with many organic solvents and other polymers.
It should be noted that the properties of specific hydroxypropyl cellulose may vary depending on the manufacturer, product grade and use, so it needs to be evaluated based on actual conditions in specific applications.
| Items | Specification |
| Hydroxypropoxy (WT%) | 5.0-16.0 |
| Loss on drying (%) | ≤ 5.0 |
| Chloride (%) | ≤ 0.36 |
| Residue on ignition (WT%) | ≤ 0.5 |
| Heavy Metals (ppm) | ≤ 10 |
Application:
Hydroxypropylcellulose (HPMC) is a versatile synthetic polymer with wide applications in many fields. The following is a brief summary of the general uses of hydroxypropyl cellulose:
Pharmaceutical industry: In the pharmaceutical industry, hydroxypropylcellulose is often used as a coating agent for tablets to improve the taste, stability and dissolution characteristics of tablets. In addition, it can also be used as a thickener and thickener for eye drops, eye ointments, ointments and other preparations.
Building materials: In building materials, hydroxypropyl cellulose is often used as a thickener and adhesive for cement mortar, gypsum mortar, tile adhesive, etc. to improve the adhesion and processing performance of the material.
Personal care products: In personal care products, hydroxypropyl cellulose is often used as a thickening agent and thickener in shampoo, conditioner, body lotion and other products.
Food industry: In the food industry, hydroxypropyl cellulose can be used as a stabilizer and thickener for dairy products, baked goods, frozen foods, etc.
In general, hydroxypropyl cellulose is widely used in pharmaceuticals, building materials, personal care products and food industries due to its good solubility, thickening and stability.
Certificate
The products have been approved by FDA,REACH,ROSH,ISO and other certification, in line with national standards.
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Packing
1kg/ bag; 25kg/ barrel;
20 tons/1×20‘FCL Shipment.
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